Introduction:Purpose and Scope of the Symposium＆BERNARD D．DAVIS

Part Ⅰ:The Origin of Enzymes＆Chairman:Bernard D．Davis

1．Remarks on the Mechanism of Enzyme Induction＆JACQUES MONOD

2．Enzymes in Cellular Differentiation＆BORIS EPHRUSSI

Added Comment＆MELVIN COHN

General Discussion＆BERNARD D．DAVIS,JACQUES MONOD,SOL SPIEGELMAN,CARL C．LINDEGREN,BORIS EPHRUSSI

3．Nucleic Acids and Enzyme Synthesis＆ERNEST F．GALE

4．On the Nature of the Enzyme-Forming System＆SOL SPIEGELMAN

Added Comment＆SIDNEY F．VELICK

General Discussion＆BERNARD D．DAVIS,SOL SPIEGELMAN,JACQUES MONOD,BORIS ROTMAN,ERNEST F．GALE,ARTHUR B．PARDEE,EDWARD L．TATUM,A．D．HERSHEY,MELVIN COHN,MAHLON B．HOAGLAND,ALVIN MARKOVITZ

Part Ⅱ:The Status of the Gene-Enzyme Relationship＆Chairman:Edward L．Tatum

Chairman＇s Comments＆EDWARD L．TATUM

5．Genetic Structure and Function in Bacteriophage T2＆A．D．HERSHEY

6．The Genetic Organization of the Deoxyribonucleate Units Functioning in Bacterial Transformations＆ROLLIN D．HOTCHKISS

Added comment＆M．DEMEREC

General Discussion＆NORMAN H．HOROWITZ,JACQUES MONOD,EDWARD L．TATUM,BERNARD D．DAVIS,CHARLES YANOFSKY,M．DEMEREC,A．D．HERSHEY,SOL SPIEGELMAN

7．The Role of the Genes in the Synthesis of Enzymes＆NORMAN H．HOROWITZ AND MARGUERITE FLING

8．Gene Interactions in Enzyme Synthesis＆CHARLES YANOFSKY

Comments on Gene-Enzyme Relationship＆JOSHUA LEDERBERG

General Discussion＆STUART MUDD,SOL SPIEGELMAN,RUTH SAGER,NORMAN H．HOROWITZ,EDWARD L．TATUM,ROBERT J．RUTMAN,HARRY EAGLE,CYRUS LEVINTHAL,NATHAN O．KAPLAN,JACQUES MONOD

Evening Lecture

The Future of Enzyme Research＆LINUS PAULING

Part Ⅲ:Enzymes and Cell Structure＆Chairman:George H．Hogeboom

9．Electron Microscopy of Mitochondria and Other Cytoplasmic Structures＆GEORGE E．PALADE

10．Physiology of Mitochondria＆ALBERT L．LEHNINGER

11．Sedimentation and Biochemical Characteristics of Cytoplasmic Particles＆EDWARD L．KUFF AND GEORGE H．HOGEBOOM

Added Comment＆VAN R．POTTER

General Discussion＆FRITZ LIPMANN,ALBERT L．LEHNINGER,DANIEL I．ARNON,HERRICK BALTSCHEFFSKY,BRITTON CHANCE,GEORGE E．PALADE

12．Nuclear Products and Nuclear Reproduction＆DANIEL MAZIA

13．Localization of Photosynthesis in Chloroplasts＆DANIEL I．ARNON

General Discussion＆CYRUS LEVINTHAL,DANIEL MAZIA,SEVERO OCHOA,DANIEL I．ARNON,NATHAN O．KAPLAN,VERNON CHELDELIN,GEORGE E．PALADE,HENRY A．LARDY,ALBERT L．LEHNINGER,DAVID E．GREEN,FRITZ LIPMANN

Part Ⅳ:Enzymatic Basis of Some Physiological Functions＆Chairman:A．Baird Hastings

14．The Actomyosin System and its Participation in Organized Enzyme Reactions＆W．F．H．M．MOMMAERTS

15．Is Energy Transferred from ATP to Myosin at the Moment that ATP is Split?＆MANUEL F．MORALES

16．Enzymatic Aspects of Excretory Mechanisms＆JOHN V．TAGGART

Added Comment＆GILBERT H．MUDGE

General Discussion＆A．BAIRD HASTINGS,JOHN GERGELY,MANUEL F．MORALES,W．F．H．M．MOMMAERTS,SIDNEY BERNHARD

17．The Biochemistry of Visual Excitation＆GEORGE WALD

18．The Enzymatic Basis of Light Emission＆WILLIAM D．MCELROY AND ARDA GREEN

Added Comment＆BERNARD L．STREHLER

General Discussion＆GEORGE WALD,MANUEL F．MORALES,WILLIAM D．MCELROY,W．F．H．M．MOMMAERTS,DANIEL I．ARNON,BERNARD L．STREHLER,J．J．WOLKEN

Evening Lecture

Mechano-chemical Coupling in Muscle＆ALBERT SZENT-GYORGYI

Part Ⅴ．Cellular Energy Sources＆Chairman:Fritz Lipmann

19．Components of the Cytochrome System＆ELMER H．STOTZ,MARTIN MORRISON,AND GUIDO MARINETTI

20．Succinic Dehydrogenase＆THOMAS P．SINGER,EDNA B．KEARNEY,AND VINCENT MASSEY

Added Comment＆ERIC G．BALL

General Discussion＆VAN R．POTTER,THOMAS P．SINGER,FRITZ LIPMANN,RICHARD J．WINZLER,HAROLD A．NEUFELD

Chairman＇s Comments＆FRITZ LIPMANN

21．Interaction of Adenosinediphosphate with the Respiratory Chain＆BRITTON CHANCE

22．Structural and Enzymatic Pattern of the Electron Transfer System＆DAVID E．GREEN

23．Hematin Compounds in the Metabolism of Photosynthetic Tissues＆MARTIN D．KAMEN

General Discussion＆W．F．H．M．MOMMAERTS,BRITTON CHANCE,DANIEL I．ARNON,FRITZ LIPMANN,DAVID E．GREEN,GEORGE E．PALADE,J．A．BASSHAM,MANUEL F．MORALES,ALVIN NASON,RALPH W．MCKEE,RONALD ESTABROOK,EDWARD L．TATUM

Part Ⅵ:Regulation of Enzyme activity＆Chairman:Severo Ochoa

Chairman＇s Comments

24．Relations between Enzymes and Permeability (Membrane Transport) in Bacteria＆BERNARD D．DAVIS

25．Action of Drugs on Enzyme Systems＆J．H．QUASTEL

Added Comment＆EARL W．SUTHERLAND,JR．

General Discussion＆SEVERO OCHOA,BERNARD D．DAVIS,CYRUS LEVINTHAL,JACQUES MONOD,STUART MUDD,OLOV LINDBERG,ARTHUR B．PARDEE

26．Interference with Nucleic Acid Metabolism＆ARNOLD D．WELCH

27．Regulation of Enzyme Activity in Muscle During Work＆CARL F．CORI

Added Comment＆HENRY A．LARDY AND R．E．PARKS,JR．

Chairman＇s Comments＆SEVERO OCHOA,ROBIN C．BUERKI

Author Index

Subject Index