Part Ⅰ:Principles of Cell Biology and Molecular Genetics

1.General Organization of the cell

Cell concept

Structure and function of cellular organelles

2.Proteins and Enzymes

Amino acids

Proteins

Enzymes

3.The Cell Membrane

Structure of the cell membrane

Transport across the cell membrane

Membrane potential

Receptors

4.The Working Cell

Cytoskeleton and cell motility

Lysosomes

Cell surface and cell adhesion

5.The Molecular Basis of Genetics

Organization of the cell nucleus

Cell cycle

Mitosis and meiosis

Structure and properties of nucleic acids

DNA packaging and repair

DNA replication

Transcription of DNA

Genetic code

Translation and protein synthesis

Post-translational modification of proteins

Genetics of bacteria and viruses

Part Ⅱ:Medical Genetics

6.Principles of Medical Genetics

Patterns of inheritance

Genetics in disease

Risk assessment and genetic counselling

Population genetics and screening

Recombinant DNA technology as applied to medicine

7.The Genetic Consultation

Genetic consultation and history taking

Common presentations of genetic disease

8.Examples of Genetic Disease

Chromosomal disorders

Trinucleotide repeat disorders

Single gene disorders

Genetic cancer syndromes

Congenital malformations

Part Ⅲ:Self-assessment

Multiple-choice Questions

Short-answer Questions

Essay Questions

MCQ Answers

SAQ Answers

Index