PART ONE BASIC PRINCIPLES

Chapter 1 General Introduction to Chemistry of Chinese Materia Medica

1 The Conception of Chemistry of Chinese Materia Medica

2 The Application of Chemistry of Chinese Materia Medica

2.1 To Clarify Effective Compositions of Chinese Herbs

2.2 To Facilitate the Development of New Drugs

3 The Progress of Chemistry of Chinese Materia Medica

3.1 Development in Identification of Effective Compositions of Chinese Herbs

3.2 The New Development in Drug Research and Pharmaceutical Industry

3.3 The Progress in Quality Control of Chinese Herbs and their Preparations

Chapter 2 General Methods for Chemical Investigation of Chinese Herbs

1 The Biosynthetic Pathways and Classification of Chemical Constituents from Chinese Herbs

1.1 Biosynthetic Pathways

1.2 Classification of Chemical Constituents

2 The General Methods for Chemical Investigation

2.1 Extraction Methods

2.2 Isolation Methods

2.3 Structure Determination Methods

Chapter 3 Carbohydrates and Glycosides

1 Carbohydrates

1.1 Introduction

1.2 Structure and Classification

1.3 The properties of carbohydrates

2 Glycosides

2.1 Introduction

2.2 Structure and Classification

2.3 General Physicochemical Properties

3 Extraction and Isolation Methods

3.1 Extraction Methods

3.2 Isolation Methods

4 Identification

4.1 Physicochemical Identification

4.2 Chromatography Identification

5 Structure Determination

5.1 Determination of Physical Constants

5.2 Determination of Molecular Formula and Molecular Weight

5.3 Identification of Aglycones and Saccharides

5.4 Determination of the Linkage Sequence and Position in the Saccharide Moiety

5.5 Determination of the Configuration of Glycosidic Linkage

Chapter 4 Quinones

1 Introduction

2 Structure Characteristics and Classification

2.1 Benzoquinones

2.2 Naphthoquinones

2.3 Phenanthraquinones

2.4 Anthraquinones

3 Physical and Chemical Properties

3.1 Physical Properties

3.2 Chemical Properties

4 Extraction and Isolation Methods

4.1 Extraction Methods

4.2 Isolation Methods

5 Identification

5.1 Physicochemical Identification

5.2 Chromatography Identification

6 Structure Elucidation

6.1 Chemical Methods

6.2 Spectroscopic Analysis of Anthraquinones

Chapter 5 Phenylpropanoids

1 Introduction

2 Simple Phenylpropanoids

2.1 Structure and Classification

2.2 Extraction and Isolation Methods

3 Coumarins

3.1 Introduction

3.2 Structure and Classification

3.3 General Physicochemical Properties

3.4 Extraction and Isolation Methods

3.5 Identification

3.6 Structure Determination

4 Lignans

4.1 Introduction

4.2 Structure and Classification

4.3 General Physicochemical Properties

4.4 Extraction and Isolation Methods

4.5 Identification

4.6 Structure Determination

Chapter 6 Flavonoids

1 Introduction

1.1 Definition of Flavonoids

1.2 Distribution of Flavonoids

1.3 Pharmacological Activities of Flavonoids

1.4 The Biosynthesis of Flavonoids

2 Structure and Classification

2.1 Flavonoid Aglycones

2.2 Flavonoid Glycosides

3 Physical and Chemical Properties

3.1 Physical Properties

3.2 Chemical Properties

4 Extraction and Isolation Methods

4.1 Extraction Methods

4.2 Isolation Methods

5 Identification

5.1 Physicochemical Identification

5.2 TLC Identification

6 Structure Elucidation

6.1 UV

6.2 NMR

6.3 MS

6.4 An Example for Structural Determination of Flavonoids

Chapter 7 Tannins

1 Introduction

2 Structure and Classification

2.1 Hydrolysable Tannins

2.2 Condensed Tannins

2.3 Complex Tannins

3 General Physicochemical Properties

3.1 Physical Properties

3.2 Chemical Properties

4 Extraction and Isolation Methods

4.1 Extraction Methods

4.2 Isolation Methods

5 Identification

6 Structure Determination

6.1 1H-NMR

6.2 13C-NMR

6.3 MS

6.4 CD

Chapter 8 Alkaloid&s

1 Introduction

1.1 Definition of Alkaloids

1.2 Distribution of Alkaloids

1.3 Pharmacological Activities of Alkaloids

2 Structure and Classification

3 Physical and Chemical Properties

3.1 Physical Properties

3.2 Chemical Properties

4 Extraction and Isolation Methods

4.1 Extraction of Alkaloids

4.2 Isolation of Alkaloids

5 Identification

5.1 Chemical Tests

5.2 Chromatography Methods

6 Structure Determination

6.1 Chemical Methods

6.2 Spectroscopy Methods

Chapter 9 Steroids

1 Introduction

1.1 Defination and Classification of Steroids

1.2 Color Reactions of Steroids

2 Cardiac Glycosides

2.1 Introduction

2.2 Structures and Classification

2.3 Relationship between Structures of Cardiac Glycosides and Their Cardiac Activities

2.4 Physical and Chemical Properties

2.5 Extraction and Isolation of Cardiac Glycosides

2.6 Identification of Cardiac Glycosides

2.7 Spectroscopic Characters of Cardiac Glycosides

3 Bile Acids

3.1 Introduction

3.2 Structure Characters of Bile Acids

3.3 Main Properties of Bile Acids

3.4 Identification of Bile Acids

3.5 Extraction and Isolation of Bile Acids

4 C21-Steroids

5 Phytosterols

Chapter 10 Terpenoids and Volatile Oils

1 Terpenoids

1.1 Introduction

1.2 Classification and Representatives of Terpenoids

1.3 Physical and Chemical Properties

1.4 Extraction and Isolation Methods

1.5 Identification

1.6 Structure Determination

2 Volatile Oils

2.1 Introduction

2.2 The Composition

2.3 Physical and Chemical Properties

2.4 Extraction and Isolation Methods

2.5 Identification

Chapter 11 Saponins

1 Introduction

2 Structure Characters and Classification

2.1 Steroidal Saponins

2.2 Triterpenoid Saponins

3 Physical and Chemical Properties

3.1 Physical Properties

3.2 Chemical Properties

3.3 Hemolysis Property

4 Extraction and Isolation Methods

4.1 Extraction Methods

4.2 Isolation Methods

5 Identification

5.1 Physical and Chemical Identification

5.2 Chromatography Identification

6 Structure Elucidation

6.1 UV

6.2 IR

6.3 MS

6.4 NMR

Chapter 12 Other Constituents

1 Fatty Acids

1.1 Introduction

1.2 Structure Characters and Classification

1.3 Physical and Chemical Properties

1.4 Extraction and Isolation Methods

2 Organic Sulphur Compounds

2.1 Introduction

2.2 Organic Sulphur Compounds from Chinese Herbs

3 Amino Acids,Proteins,and Enzymes

3.1 Amino Acids

3.2 Proteins and Enzymes

4 Minerals

4.1 Introduction

4.2 Examples of Mineral

PART TWO APPLICATIONS

Chapter 13 Examples of Chinese Herbs

Lycii Fructus（Gouqizi）

Armeniacae Semen Amarum（Kuxingren）

Rhei Radix et Rhizoma（Dahuang）

Salviae Miltiorrhizae Radix et Rhizoma（Danshen）

Arnebiae Radix（Zicao）

Fraxini Cortex（Qinpi）

Schisandrae Chinensis Fructus（Wuweizi）

Forsythiae Fructus（Lianqiao）

Scutellariae Radix（Huangqin）

Puerariae Lobatae Radix（Gegen）

Sophorae Flos（Huaihua）

Ginkgo Folium（Yinxingye）

Galla Chinensis（Wubeizi）

Cinnamomi Cortex（Rougui）

Ephedrae Herba（Mahuang）

Coptidis Rhizoma（Huanglian）

Daturae Flos（Yangjinhua）

Sophorae Flavescentis Radix（Kushen）

Stephaniae Tetrandrae Radix（Fangji）

Corydalis Rhizoma（Yanhusuo）

Periplocae Cortex（Xiangjiapi）

Bufonis Venenum（Chansu）

Bovis Calculus（Niuhuang）

Artemisiae Annuae Herba（Qinghao）

Andrographis Herba（Chuanxinlian）

Rehmanniae Radix（Dihuang）

Menthae Haplocalycis Herba（Bohe）

Ginseng Radix et Rhizoma（Renshen）

Glycyrrhizae Radix et Rhizoma（Gancao）

Bupleuri Radix（Chaihu）

Ophiopogonis Radix （Maidong）

Allii Sativi Bulbus（Dasuan）

APPENDICES

Appendix Ⅰ Glossary

Appendix Ⅱ Latin Names

Appendix Ⅲ Abbreviations for Commonly Used Solvents