Ⅰ.BASIC PRINCIPLES

1．Introduction Bertram G.Katzung,MD,PhD

2．Drug Receptors Pharmacodynamics Henry R.Bourne,MD, Mark von Zastrow,MD,PhD

3．Pharmacokinetics Pharmacodynamics:Rational Dosing the Time Course of Drug Action Nicholas H.G.Holford,MB,ChB,FRACP

4．Drug Biotransformation Maria Almira Correia,PhD

5．Basic Clinlcal Evaluation of New Drugs Barry A.Berkowitz,PhD, Bertram G.Katzung,MD,PhD

Ⅱ.AUTONOMIC DRUGS

6．Introduction to Autonomic Pharmacology Bertram G.Katzung,MD,PhD

7．Cholinoceptor-Activating Cholinesterase-Inhibiting Drugs Achilles J.Pappano,PhD,

8．Cholinoceptor-Blocking Drugs Achilles J.Pappano,PhD, Bertram G.Katzung,MD,PhD

9．Adrenoceptor-Activating Other Sympathomimetlc Drugs Brian B.Hoffman,MD

10．Adrenoceptor Antagonist Drugs Brian B.Hoffman,MD

Ⅲ.CARDIOVASCULAR-RENAL DRUGS

11．Antihypertenslve Agents Neal L.Benowitz,MD

12．Vasodilators the Treatment of Angina Pectorls Bertram G.Katzung,MD,PhD, Kanu Chatterjee,MB,FRCP

13．Cardiac Glycosides Other Drugs Used in Congestive Heart Failure Bertram G.Katzung,MD,PhD, William W.Parmley,MD

14．Agents Used in Cardiac Arrhythmias Luc M.Hondeghem,MD,PhD, Dan M.Roden,MD

15．Diuretic Agents Harlan E.Ives,MD,PhD

16．Histamine,Serotonin, the Ergot Alkaloids Bertram G.Katzung,MD,PhD, David J.Julius,PhD

Ⅳ.DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE

17．Vasoactive Peptides Ian A.Reid PhD

18．The Eicosanoids:Prostaglandins,Thromboxanes,Leukotrienes, Related Compounds Marie L.Foegh,MD,DSc, Peter W.Ramwell,PhD

19．Nitric Oxide,Donors, Inhibitors George Thomas,PhD, Peter W.Ramwell,PhD

20．Drugs Used in Asthma Homer A.Boushey,MD

Ⅴ.DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM

21．Introduction to the Pharmacology of CNS Drugs Roger A.Nicoll,MD

22．Sedative-Hypnotic Drugs Anthony J.Trevor,PhD, Walter L.Way,MD

23．The Alcohols Susan B.Masters,PhD

24．Antiselzure Drugs Roger J.Porter,MD, Brian S.Meldrum,MB,PhD

25．General Anesthetics Anthony J.Trevor,PhD, Ronald D.Miller,MD

26．Local Anesthetics Ronald D.Miller,MD, Bertram G.Katzung,MD,PhD

27．Skeietal Muscle Relaxants Ronald D.Miller,MD, Bertram G.Katzung,MD,PhD

28．Pharmacologic Management of Parkinsonism Other Movement Disorders Michael J.Aminoff,MD,FRCP

29．Antipsychotic Agents Lithium William Z.Potter,MD,PhD, Leo E.Hollister,MD

30．Antidepressant Agents William Z.Potter,MD,PhD, Leo E.Hollister,MD

31．Opioid Analgesics Antagonists Walter L.Way,MD,Howard L.Fields,MD,PhD, Mark A.Schumacher,PhD,MD

32．Drugs of Abuse Thomas R.Kosten,MD,and Leo E.Hollister,MD

Ⅵ.DRUGS USED TO TREAT DISEASES OF THE BLOOD,INFLAMMATION, GOUT

33．Agents Used in Anemias;Hematopoietic Growth Factors Daniel V.Santi,MD,PhD, Susan B.Masters,PhD

34．Drugs Used in Disorders of Coagulation Julie Hambleton,MD, Robert A.O Reilly,MD

35．Agents Used in Hyperlipidemia Mary J.Malloy,MD, John P.Kane,MD,PhD

36．Nonsteroidal Anti-Inflammatory Drugs,Disease-Modifying Antirheumatic Drugs,Nonopioid Analgesics, Drugs Used in Gout Daniel E.Furst,MD, Tino Munster,MD

Ⅶ.ENDOCRINE DRUGS

37．Hypothalamic Pituitary Hormones Paul A.Fitzgerald,MD

38．Thyroid Antithyroid Drugs Francls S.Greenspan,MD, Betty J.Dong,PharmD

39．Adrenocorticosteroids Adrenocortical Antagonists George P.Chrousos,MD, Andrew N.Margioris,MD

40．The Gonadal Hormones Inhibitors George P.Chrousos,MD,Emmanouil N.Zoumakis,PhD, Achille Gravanis,PhD

41．Pancreatic Hormones Antidlabetic Drugs Martha S.Nolte,MD, John H.Karam,MD

42．Agents That Affect Bone Mineral Homeostasls Daniel D.Bikle,MD,PhD

43．Beta-Lactam Antibiotics Other Inhibitors of Cell Wall Synthesis Henry F.Chambers,MD

Ⅷ.CHEMOTHERAPEUTIC DRUGS

44．Chloramphenicol,Tetracyclines,Macrolldes,Clindamycin, Streptogramins Henry F.Chambers,MD

45．Aminoglycosides Spectinomycin Henry F.Chambers,MD

46．Sulfonamides,Trimethoprim, Quinolones Henry F.Chambers,MD

47．Antimycobacterial Drugs Henry F.Chambers,MD

48．Antifungal Agents Don Sheppard,MD, Harry W.Lampiris,MD

49．Antiviral Agents Sharon Safrin,MD

50．Miscellaneous Antimicrobil Agents;Disinfectants,Antiseptics, Steriiants Henry F.Chambers,MD

51．Clinical Use of Antimicrobial Agents Harry W.Lampiris,MD, Daniel S.Maddix,PharmD

52．Basic Principies of Antiparasitic Chemotherapy Ching Chung Wang,PhD

53．Antiprotozoal Drugs Philip J.Rosenthal,MD, Robert S,Goldsmith,MD,DTM H

54．Clinical Pharmacology of the Anthelmintic Drugs Robert S.Goldsmith,MD,DTM H

55．Cancer Chemotherapy Sydney E.Salmon,MD, Alan C.Sartorelli,PhD

56．Immunopharmacology Douglas F.Lake,PhD,Emmanuel T.Akporiaye,PhD, Evan M.Hersh,MD

Ⅸ.TOXICOLOGY

57．Introduction to Toxicology:Occupational Environmental Gabriel L.Plaa,PhD

58．Heavy Metal Intoxication Chelators Michael J.Kosnett,MD,MPH

59．Management of the Poisoned Patlent Kent R.Olson,MD

60．Special Aspects of Perinatal Pediatric Pharmacology Gideon Koren,MD

Ⅹ.SPECIAL TOPICS

61．Special Aspects of Geriatric Pharmacology Bertram G.Katzung,MD,PhD

62．Dermatologic Pharmacology Dirk B.Robertson,MD, Howard I.Maibach,MD

63．Drugs Used in Gastrointestinal Diseases David F.Altman,MD

64．Therapeutic Toxic Potential of Over-the-Counter Agents Robin L.Corelli,PharmD, Mary Anne Koda-Kimble,PharmD

65．Botanicals( Herbal Medications ) Nutritional Supplements Cathi E.Dennehy,PharmD, Candy Tsourounis,PharmD

66．Rational Prescribing Prescription Wrlting Paul W.Lofholm,PharmD, Bertram G.Katzung,MD,PhD

AppendixⅠ. Vaccines,Immune Globulins, Other Compiex Biologic Products Harry W.Lampiris,MD, Daniel S.Maddix,PharmD

AppendixⅡ. Important Drug Interactions Their Mechanisms Phillp D.Hansten,PharmD

Index