Part I:Principles of Pathology

Preface

1.Introduction to Pathology

Disease

Pathology

How pathology is covered in this book

Acknowledgements

2.Cancer

Definitions and nomenclature

Molecular basis of cancer

Dedication

Tumour growth

Carcinogenic agents

Host defences against cancer

3.Inflammation, Tissue Damage and Repair

Inflammation

Acute inflammation

Chemical mediators of inflammation

Chronic inflammation

Tissue necrosis

4.Infectious Disease

General principles of infection

Categories of infectious agents

Mechanisms of pathogenicity

Inflammatory responses to infection

Molecular basis of inherited disease

5.Inherited Disease

Chromosomal disorders

Non-Mendelian inheritance

Part II:Systemic Pathology

6.Pathology of the Nervous System

Disorders of the Central Nervous System

Disorders of the Peripheral Nervous System

Disorders of the Autonomic Nervous System

7.Pathology of the Cardiovascular System

Congenital abnormalities of the heart

Atherosclerosis, hypertension and ischaemic heart disease

Disorders of the heart valves

Diseases of the myocardium

Diseases of the pericardium

Aneurysms

Inflammatory and neoplastic vascular disease

Diseases of the veins and lymphatics

8.Pathology of the Respiratory System

Disorders of the Upper Respiratory Tract

Disorders of the Lungs

Disorders of the Pleura

9.Pathology of the Gastrointestinal System

Disorders of the upper gastrointestinal tract

Disorders of the stomach

General aspects of hepatic damage

Disorders of the liver and biliary tract

Disorders of the exocrine pancreas

Disorders of the intestine

Disorders ofthe peritoneum

10.Pathology of the kidneys and Urinary Tract

Abnormalities of kidney structure

Diseases of the glomerulus

Glomerular lesions in systemic disease

Diseases of the tubules and interstitium

Diseases ofthe renal blood vessels

Neoplastic disease of the kidney

Disorders of the urinary tract

11.Pathology of the Endocrine System

Disorders of the pituitary

Thyroid disorders

Graves disease

Parathyroid disorders

Disorders of the adrenal gland

Disorders of the endocrine pancreas

12.Pathology of the Reproductive Systems

Disorders of the vulva, vagina and cervix

Disorders of the uterus and endometrium

Disorders of the ovary and fallopian tubes

Disorders of the placenta and pregnancy

Disorders of the breast

Disorders of the male reproductive system

13.Pathology of the Musculoskeletal System

Disorders of the bone structure

Infections and trauma

Tumours of the bones

Disorders of the neuromuscular junction

The myopathies

Arthropathies

14.Pathology of the Blood and Immune System

Autoimmune disease

Diseases of immune deficiency

Amyloidosis

Disorders of white blood cells and lymph nodes

Disorders of the spleen and thymus

Disorders of red blood cells

Disorders of haemostasis

Terminology of skin pathology

15.Pathology of the Skin

Inflammation and skin eruptions

Infections and infestations

Disorders of specific skin structures

Disorders of pigmentation

Blistering disorders

Tumours of the skin

Part III:Self-assessment

Multiple-choice Questions

Short-answer Questions

Essay Questions

MCQ Answers

SAQ Answers

Index